Garber Janet C. et al. Guide for the Care and Use of Laboratory Animals

Washington: The National Academies Press, 2010. — 218 p.The Guide for the Care and Use of Laboratory Animals (the Guide) was first published in 1963 under the title Guide for Laboratory Animal Facilities and Care and was revised in 1965, 1968, 1972, 1978, 1985, and 1996. More than 550,000 copies have been printed since its first publication. The Guide is an internationally accepted primary reference on animal care and use. Use of the Guide is required by the Public Health Service Policy.
The purpose of the Guide, as expressed in the charge to the Committee to Update the Guide for the Care and Use of Laboratory Animals, is to assist institutions in caring for and using animals in ways judged to be scientifically, technically, and humanely appropriate. The Guide is also intended to assist investigators in fulfilling their obligation to plan and conduct animal experiments in accord with the highest scientific, humane, and ethical principles. The recommendations are based on published data, scientific principles, expert opinion, and experience with methods and practices that have proved to be consistent with high-quality humane animal care and use. These recommendations should be used as a foundation for the development of a comprehensive animal care and use program, recognizing that the concept and application of performance standards, in accordance with goals, outcomes and considerations defined in the Guide, is essential to this process.