Wynn Robert, Bhat Rukhmi, Monagle Paul. Pediatric Hematology. A Practical Guide

Cambridge University Press, 2017. — 289 p. — ISBN: 978-1-107-43936-8.This book is for all those who have contact with pediatric hematology – medical students, doctors-in-training, nurses, pharmacy staff, and patients and their families. We, as clinicians and here as authors, spend much of our time explaining the principles and practice of our subject, making it easy to understand. This book summarizes that teaching. Each chapter covers a single area of our subject and follows a standard format, including a summary of the key disease-related points. Understanding the chapter will allow the student or practitioner to understand his or her patient, the family to understand better the illness affecting their child, and the exam candidate to deal with pediatric hematology to a postgraduate level (with the book chapters mirroring international exam syllabuses). There are separate clinical scenarios that detail the practical management of several common hematologic situations, including newly diagnosed leukemia and its emergency situations, the child with pancytopenia, and the child with neutropenia and fever. These scenarios complement the didactic chapters, encouraging readers to manage effectively the more common problems in both a patient- and problem-oriented manner.Hematology is often considered a challenging subject by students and junior medical staff alike. Using key scientific and clinical principles, this succinct guide provides a summary of modern day-to-day clinical practice in paediatric hematology. Focusing on the facts that underpin patient management, each chapter offers an initial summary of a particular paediatric hematologic condition. Several key clinical scenarios set out how common difficulties should be managed, from the neonate with line thrombosis, to the newly presenting patient with leukaemia, and the child who has suffered a stroke. Covering all hematology topics on the syllabus of the American Board of Paediatrics subspecialty examinations, this authoritative guide is ideal for both postgraduates and junior doctors, whose understanding of hematological conditions will increase greatly upon reading. This comprehensive and practical book specifically aims to equip clinicians to diagnose and manage children with hematological illness, and to support them and their families.Normal Hemopoiesis and the Physiology of Blood
The Coagulation System
Common Laboratory Tests Used in Hematology and How to Interpret Them
Reference Ranges in Children
Neonatal Anemia
Neonatal Abnormal Myelopoiesis and the Hematology of Down Syndrome
Neonatal Thrombocytopenia
Neonatal Bleeding Disorders
Neonatal Thrombotic Disorders
Inherited Bone Marrow Failure Syndromes
Acquired Bone Marrow Failure Syndrome: Aplastic Anemia
Sideroblastic Anemias
Iron Deficiency
Disorders of Vitamin B12 and Folate
Hemolytic Anemia
Infections in Hematology Patients and the Hematologic Features of Infectious Disease
Sickle Cell Disease
Thalassemia
Neutropenia
Neutrophil Function Disorders
Clinical Scenario 1: The Child with Newly Presenting Acute Leukemia
Clinical Scenario 2: Hyperleukocytosis
Clinical Scenario 3: Management of the Child with a Mediastinal Mass
Clinical Scenario 4: Approach to the Neutropenic Child with Fever
Clinical Scenario 5: Approach to the Child with Pancytopenia
Clinical Scenario 6: Does This Child Have Lymphoma?
Clinical Scenario 7: Diamond-Blackfan Anemia, Transient Erythroblastopenia, or Other Cause of Red Cell Aplasia in Children
Clinical Scenario 8: Approach to Evaluation for a Bleeding Disorder in a Child with Suspected Inflicted or Nonaccidental Injury
Clinical Scenario 9: The Neonate with Catheter-Related Thrombosis
Clinical Scenario 10: Neonatal Renal Vein Thrombosis
Inherited Thrombocytopenia
Acquired Thrombocytopenia and Immune Thrombocytopenic Purpura (ITP)
Immune Deficiency
Hemophagocytic Lymphohistiocytosis (HLH) and Other Nonmalignant Histiocytic Disorders
Osteopetrosis
Hemophilia
Congenital and Acquired von Willebrand Disease Rare Inherited Bleeding Disorders
Acquired Bleeding Disorders
Venous Thrombosis in Children
Arterial Thrombosis in Children
Stroke in Children
Anticoagulation in Children
Blood Transfusion: Indications and Safe Use in Children
Adverse Reactions to Blood Products and Special Transfusion Circumstances
Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Juvenile Myelomonocytic Leukemia (JMML) and Myelodysplastic Syndromes (MDS)
Principles of Blood and Marrow Transplantation (BMT) in Pediatric Medicine