Pevsner J. Bioinformatics and Functional Gemomics

Wiley, John & Sons, 2009. — 971 p.Introduction to Bioinformatics provides a broad-based introduction to bioinformatics by following three, real-world examples throughout the book: retinol-binding protein, breast cancer, and a calcium binding site C. The author emphasizes the use of computational tools and databases to study connections between the structure of proteins and genes to function, development, evolution, and disease. Readers will learn real skills, such as how to analyze genes and proteins, how to make trees using phylogenetic software, how to extract data, or how to identify genes and proteins implicated in diseases.Preface to the Second Edition

ForewordAccess to Sequence Data and Literature Information,
Pairwise Sequence Alignment,
Basic Local Alignment Search Tool (BLAST),
Advanced Database Searching,
Multiple Sequence Alignment,
Molecular Phylogeny and Evolution,Bioinformatic Approaches to Ribonucleic Acid (RNA),
Gene Expression: Microarray Data Analysis,
Protein Analysis and Proteomics,
Protein Structure,
Functional Genomics,Completed Genomes,
Completed Genomes: Viruses,
Completed Genomes: Bacteria and Archaea,
The Eukaryotic Chromosome,
Eukaryotic Genomes: Fungi,
Eukaryotic Genomes: From Parasites to Primates,
Human Genome,
Human Disease,Answers to Self-Test Quizzes,