Mukhopadhyay A. (ed.) Regenerative Medicine: Laboratory to Clinic

Singapore: Springer, 2017. — 536 p.This book discusses the two different cellular approaches that are pursued in regenerative medicine: cell therapy and tissue engineering. It examines in detail the therapeutic application of hematopoietic stem cells in marrow regeneration, multi-potent mesenchymal stem cells (MSCs), also referred to as mesenchymal stromal cells. The interest in MSCs can be seen in more than 150 clinical trials, some of which have progressed to Phase III, despite the cells’ limited differentiation potential. The book also explores how embryonic stem (ES) cells, being pluripotent in nature, can resolve some of the problems associated with adult stem cells, yet entail other challenges like risks of teratoma formation and immune rejection. A separate chapter deals with the role of noncoding RNAs in neuronal commitment of induced pluripotent stem (iPS) cells.
Chapters like “Cord blood banking in India and the global scenario”; “3D bioprinting of tissue” and others will make this book an extremely interesting read for all students, researchers and clinicians working in the area of regenerative medicine/stem cells.
The book is broadly divided into two parts, the first of which is devoted to basic information on stem cells, and the second of which addresses potential clinical applications in the areas of hematology, cardiology, orthopedic and immune suppression, etc.Impact of the Diabetic State on Wound Healing Dynamics and Expression of Soluble Cellular Mediators
Etiology and Treatment of Osteoarthritis: A Developmental Biology Perspective
Unraveling the Role of Long Noncoding RNAs in Pluripotent Stem Cell-Based Neuronal Commitment and Neurogenesis
Physico-Chemical Properties of the Stem Cell Niche
Human Mesenchymal Stem Cell (hMSC) -Derived Exosomes/Exosome Mimetics as a Potential Novel Therapeutic Tool for Regenerative Medicine
To D(e)rive or Reverse: The Challenge and Choice of Pluripotent Stem Cells for Regenerative Medicine
Human Gingiva: A Promising Source of Mesenchymal Stem Cells for Cell Therapy and Regenerative Medicine
Transdifferentiation: A Lineage Instructive Approach Bypassing Roadways of Induced Pluripotent Stem Cell (iPSC)
Ideal Stem Cell Candidate for Regenerative Medicine: Pluripotent Stem Cells, Adult Stem Cells, or Pluripotent Stem Cells in Adult Organs?Pancreatic Progenitors as Target for Islet Neogenesis to Manage Diabetes
Cell Therapy in Liver Diseases
Regeneration of Lacrimal Gland: Potential and Progress
Hype and Hopes of Stem Cell Research in Neurodegenerative Diseases
Cartilage Tissue Engineering: Scaffold, Cell, and Growth Factor-Based Strategies
Silk-Based Bioinks for 3D Bioprinting
Potentials of Cord Blood Use in Transfusion Medicine
Umbilical Cord Blood Banking: Indian Standing in Global Scenario
Prospects and Retrospect of Clinical Applications of Stem Cells in Veterinary Animals
Preclinical Study: A Bottleneck Impedes the Progress of Regenerative Medicine
Thriving for the Renewal of Life: Present Needs in Cell Therapy Translational ResearchAllogeneic Stem Cell Transplantation for Thalassemia Major
Clinical Trials of Cardiac Regeneration Using Adult Stem Cells: Current and Future Prospects
Corneal Regeneration: Current Status and Future Prospective
Mesenchymal Stem Cells and Transplantation Tolerance
Designing Bioactive Scaffolds for Dental Tissue Engineering
Blood to Blood: A New Therapeutic Opportunity for Age-Related Diseases
Physeal Regeneration: From Bench to Bedside
Mesenchymal Stromal Cells: Emerging Treatment Option for Diabetic Wounds
Idiopathic Pulmonary Fibrosis: Stem Cell-Mediated Therapeutic Approach