6th edition. — Lippincott Williams & Wilkins Health, 2013. — 2109 p.
Hemostasis and Thrombosis has established itself as the pre-eminent book in the field of coagulation disorders. No other book is as inclusive in scope, with coverage of the field from the standpoint of both basic scientists and clinicians. This comprehensive resource details the essentials of bleeding and thrombotic disorders and the management of patients with these and related problems, and delivers the most up-to-date information on normal biochemistry and function of platelets or endothelial cells, as well as in-depth discussions of the pharmacology of anticoagulant, fibrinolytic, and hemostatic drugs.
Introduction to the Field of Hemostasis and ThrombosisHistory of the Field
Molecular Evolution of the Vertebrate Blood Coagulation System
Molecular and Clinical Genetics
Coagulation Enzymology
Cell Biology, Protein Processing, and Cell Signaling
Cellular and Molecular Immunology
Biostatistics and Epidemiology: The Basic Science of Clinical Research
BASIC HEMOSTASIS AND THROMBOSISCOAGULATION & FIBRINOLYSISOverview of Basic Coagulation and Fibrinolysis
The Blood Coagulation Factors and Inhibitors: Complementary DNAs, Genes and Expression
Genetics of Coagulation Proteins
Tissue Factor and the Initiation and Regulation (TFPI) of Coagulation
Factors V and VIII
Structure and Function of von Willebrand Factor
Structure and Function of Vitamin K-Dependent Coagulant and Anticoagulant Proteins
Factor XI
The Factor XII-driven Plasma Contact System
Fibrinogen Structure and Function