Grzybowski A., Barboni P. (eds.) OCT in Central Nervous System Diseases: The Eye as a Window to the Brain

New York: Springer, 2017. — 343 p.This book reviews recent important advances in the use of optical coherence tomography (OCT) in order to analyze neurodegeneration within the retina through the quantification of axonal loss. Detailed information is provided on the role of OCT as a promising tool for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. The disorders considered include multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the “window to the brain”.Introduction: Retina Imaging – Past and Present
OCT Technique – Past, Present and Future
Optical Coherence Tomography and Optic Nerve Edema
OCT and Compressive Optic Neuropathy
Optical Coherence Tomography (OCT) and Multiple Sclerosis (MS)
OCT and Parkinson’s Disease
Optical Coherence Tomography in Alzheimer’s Disease
Friedreich’s Ataxia and More: Optical Coherence Tomography Findings in Rare Neurological Syndromes
Other Neurological Disorders: Migraine, Neurosarcoidosis, Schizophrenia, Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS)
Hereditary Optic Neuropathies
Trans Neuronal Retrograde Degeneration to OCT in Central Nervous System Diseases
OCT in Toxic and Nutritional Optic Neuropathies
Animal Models in Neuro Ophthalmology
Optical Coherence Tomography (OCT) in Glaucoma
OCT in Amblyopia
Conclusion: The Exciting Future of OCT Imaging of Retina