Ruebusch Mary, Daugherty Steven R. — DeVry / Becker Professional Education, 2013. — 454 p.
Immunology.
Overview of Immunity.
Components of the Immune System.
The Design of the Immune System.
The Birth of the Immune Response.
Origin of Immune Cells.
The Cells of the Immune System.
Development of Antigen Recognition Molecules.
Selection of Lymphocyte Receptors.
Review Questions: Chapters.
Immunologic Surveillance: Lymphocyte Recirculation.
Overview of Lymphocyte Recirculation.
Secondary Lymphoid Organs.
The Battle Begins: Acute Inflammation.
Overview of Acute Inflammation.
Chemotaxis.
Diapedesis.
Recognizing Nonself.
Phagocytosis.
Processing and Presentation of Antigens.
Overview of Antigen-Presenting Cells.
Pathways for Loading MHC Molecules With Peptides.
Transportation of Antigen to Secondary Lymphoid Organs.
Differentiation of Macrophage Populations.
Activation of T Helper Cells.
Differentiation of T Helper Cell Subsets.
Review Questions: Chapters.
Humoral Immunity.
Overview of Humoral Immunity.
T Cell Independent B Cell Activation.
T Cell Dependent B Cell Activation.
Class Switching.
Affinity Maturation.
Isotype Switching.
Complement.
Cell-Mediated Immunity.
Overview of Cell-Mediated Immunity.
Effector Cells of CMI.
Immunologic Memory.
Overview of Immunologic Memory.
Activation-Induced Cell Death.
Characteristics of Memory Cells.
Dissemination of Memory.
Comparison of Primary and Subsequent I mmune Responses.
Review Questions: Chapters.
lmmunoprophylaxis and Immunotherapy.
Forms of Immunologic Therapy.
Active Immunization.
Passive Immunotherapy.
Immunodeficiency Diseases.
Primary Immunodeficiencies.
Acquired Immunodeficiencies: HIV/AIDS.
Review Questions: Chapters.
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Immunology.
Hypersensitivity and Autoimmunity.
Overview of Hypersensitivity and Autoimmunity.
Type I Hypersensitivity.
Type II Hypersensitivity.
Type III Hypersensitivity.
Type IV Hypersensitivity.
Pathogenesis of Autoimmunity.
Therapy of Hypersensitivities and Autoimmune Diseases.
Transplantation Immunology.
Overview of Transplantation Immunology.
Mechanisms of Transplant Rejections.
Tissue Compatibility Testing.
Uses of Immunology in Diagnostic Medicine.
Precipitation and Agglutination Reactions.
Immunofluorescent Assays.
Radioimmunoassay (RIA) and Enzyme-linked Immunoassay (EIA).
Western Blot.
Fluorescence-Activated Cell Sorter.
Review Questions: Chapters.
Clinical Cases...C.
Appendix 1 Cytokines...A.
Appendix 2 CD Markers... A.
Appendix 3 Cell Adhesion Molecules... A.
Appendix 4 The Immune Response in Infection.