Islam M.S. (ed.) Calcium Signaling

Amsterdam: Springer, 2012. — 1253 p.Calcium signaling contains a unique selection of chapters that cover a wide range of contemporary topics in this ubiquitous and diverse system of cell signaling. This book has the flavor of a primary text book, but it is much more than that. It covers topics ranging from the fundamental aspects of calcium signaling to its clinical implications, in a thoughtful and comprehensive way. It discusses cutting edge researches, and critical issues at depth, and it presents many testable hypotheses for future research. It includes the theoretical and the methodological topics as well as topics related to mathematical modeling, and simulations. If you want to read about calcium signaling in different mammalian cells, oocytes, Zebrafishes, and even in plants, in one and the same book, then this book will not disappoint you. From the beginners to the experts in the field of calcium signaling, everybody will find something useful in this very timely book.The Regulation of a Cell’s Ca 2+ Signaling Toolkit: The Ca 2+ Homeostasome
Methods to Detect Ca 2+ in Living Cells
Development and Optimization of FLIPR High Throughput Calcium Assays for Ion Channels and GPCRs
Two-Photon Calcium Imaging in the Intact Brain
Signaling Through the Extracellular Calcium-Sensing Receptor (CaSR)
Ca 2+ Signaling: An Outlook on the Characterization of Ca 2+ Channels and Their Importance in Cellular Functions
Ryanodine Receptor Calcium Release Channels: An Evolutionary Perspective
Techniques and Methodologies to Study the Ryanodine Receptor at the Molecular, Subcellular and Cellular Level
Ryanodine Receptor Physiology and Its Role in Disease
Phospholipase C
Inositol 1,4,5-Trisphosphate and Its Receptors
The Discovery and Structural Investigation of the IP 3 Receptor and the Associated IRBIT Protein
Pyridine Nucleotide Metabolites and Calcium Release from Intracellular Stores
NAADP on Target
Store-Operated Ca 2+ Entry
Structure, Regulation and Biophysics of I CRAC , STIM/Orai1
Mitochondria-Associated Membranes (MAMs) as Hotspot Ca 2+ Signaling Units
Calcium Around the Golgi Apparatus: Implications for Intracellular Membrane Trafficking
Calcium Binding Proteins
Cytoplasmic Calcium Buffering
Elementary Calcium Release Events from the Sarcoplasmic Reticulum in the Heart
Calcium Oscillations and Pacemaking
Calcium Oscillations and Waves in Cells
Calcium Signaling: From Single Channels to Pathways
Simulation Strategies for Calcium Microdomains and Calcium-Regulated Calcium Channels
Combined Computational and Experimental Approaches to Understanding the Ca 2+ Regulatory Network in Neurons
α7 Nicotinic ACh Receptors as a Ligand-Gated Source of Ca 2+ Ions: The Search for a Ca 2+ Optimum
The Biology of Protein Kinase C
The Role of C2 Domains in PKC Signaling
Ca 2+ /Calmodulin-Dependent Protein Kinase II (CaMKII) in the Heart
The Role of Molecular Regulation and Targeting in Regulating Calcium/Calmodulin Stimulated Protein Kinases
Calcium Sensing in Exocytosis
Regulation of Voltage-Gated Calcium Channels by Synaptic Proteins
Regulation of Intercellular Calcium Signaling Through Calcium Interactions with Connexin-Based Channels
Calcium Signaling in Vascular Smooth Muscle Cells: From Physiology to Pathology
Calcium and Endothelium-Mediated Vasodilator Signaling
Calcium Signaling in Cerebral Vasoregulation
Ca 2+ Signaling Mechanisms in Bovine Adrenal Chromaffin Cells
Calcium Stores in Vertebrate Photoreceptors
Stem Cells and Calcium Signaling
Calcium Signaling in Osteoclast Differentiation and Bone Resorption
Calcium Signaling in Renal Tubular Cells
Calcium in Epidermis
Calcium Signaling in Mast Cells: Focusing on L-Type Calcium Channels
Proteinase-Activated Receptors (PARs) and Calcium Signaling in Cancer
Mechanosensory Calcium Signaling
Role Ca 2+ in Mechanisms of the Red Blood Cells Microrheological Changes
Calcium Imaging in the Zebrafish
Calcium Signaling in Xenopus oocyte
Calcium Oscillations, Oocyte Activation, and Phospholipase C zeta
Nuclear Calcium Signaling and Its Involvement in Transcriptional Regulation in Plants
Remodeling of Calcium Handling in Human Heart Failure
Proarrhythmic Atrial Calcium Cycling in the Diseased Heart
Neuronal Calcium Signaling and Alzheimer’s Disease
Voltage-Gated Ca 2+ Channel Mediated Ca 2+ Influx in Epileptogenesis