Piscitelli S.C., Rodvold K.A. (eds.) Drug interactions in infectious diseases

Humana Press, 2005. — 534 p.
Drug interactions in the field of infectious diseases continue to expand as new drugs are approved, new mechanisms are identified, and recommendations for co-administration of drugs are revised. The editors of Drug Interactions in Infectious Diseases are gratified that the first edition was well received and we are enthusiastic about the additions and improvements to this second edition.
Major changes have taken place in our understanding of interaction mechanisms. The literature on P-glycoprotein and other transporters has dramatically increased since the first edition. There is so much new knowledge on transport proteins that an entire chapter has been devoted to this issue. We have also included a chapter outlining the regulatory perspective on interaction studies in drug development since guidances from various countries have been put forth. In addition to these new chapters, our authors have updated their chapters to include new drugs that have become available since the first edition. This is especially true in the field of HIV infection, where several new drugs have been approved over the past three years. Finally, the aspects of this text that make it unique are once again present. The chapter on study design and data analysis is one of the best of its kind. New cases have been added to each chapter and highly acclaimed chapters, such as food interactions and drug–cytokine interactions, are updated and revised.