Ciurtin C., Isenberg D. (Eds.) Biologics in Rheumatology: New Developments, Clinical Uses and Health Implication

Nova Science Publishers, Inc., NY, USA, 2016. — 541 p. — ISBN10: 1634852745.Significant progress has recently been achieved in the treatment of many autoimmune rheumatic diseases (ARD) with the introduction of biologic treatments, which target specific molecules implicated in their pathogenesis. In the past two decades, these developments have substantially improved the long-term outcome of patients with ARD, both in terms of their survival rates and quality of life. The principal biologic approaches in clinical use include biologic agents that (a) interfere with cytokine function, (b) inhibit the "co-stimulatory signal" required for T cell activation and (c) deplete the circulatory B cells. The first rheumatic condition that benefitted from the introduction of the biologic agents was rheumatoid arthritis, and following the great therapeutic success of this approach, the majority were subsequently tested in other autoimmune diseases.Biologic Treatments in Autoimmune Rheumatic Diseases
Biologic Therapies for Systemic Lupus Erythematosus
Biologics in Juvenile Systemic Lupus Erythematosus
Biologic Treatments for Idiopathic Inflammatory Myopathies
Biologic Treatment Advances in Sjӧgren’s Syndrome: Understanding the Implications of Using Biologic Therapies in Selected Categories of Patients
Biologic Therapies in Systemic Sclerosis
The Role of Biologics in the Treatment of Small and Medium Vessel Vasculitis
Imaging and Pathogenesis in Large Vessel Vasculitis: Early Lessons for Biologic Treatments
Biologics in Behçet Syndrome
Tumour Necrosis Factor Inhibitors Used in the Treatment of Rheumatoid Arthritis: Evidence of Safety, Efficacy and Health Implication
Biologic Treatments (Other than Anti-TNF Therapy) Licensed for Use in Rheumatoid Arthritis
New Biologic Agents and Biosimilars Developed for Rheumatoid Arthritis
Biologics in Spondyloarthritis
Established and New Biologic Therapies for Psoriatic Arthritis and Psoriasis
Biologics in Juvenile Idiopathic Arthritis
Biologic Disease Modifying Anti-Rheumatic Drugs in Pregnancy and Breast-Feeding Period
Biologic Therapy in Osteoporosis: New Developments, Clinical Uses and Health Implications
Biologic Treatments for Pulmonary Involvement in Rheumatic Disease
Additional Benefits of Tumour Necrosis Factor Inhibitor Therapies
Infection and Biologics
Participant Information Sheets in Clinical Research: Compromising the Ethics of Informed Consent?
Biologic Treatment: The Young Patients’ Perspective
Strategies and Safety Nets: Nurse-Led Care of the Patient on Biologics