Hatfull G.F., Jacobs W.R. Jr (Eds.) Molecular genetics of mycobacteria

ASM Press, 2014. — 824 p.
Tuberculosis, caused by Mycobacterium tuberculosis, causes one in four avoidable deaths in the developing world and kills more adults than malaria, AIDS, and all tropical diseases combined. TB is now considered a global health emergency; a distinction never accorded another disease. Although the field of mycobacterial genetics has expanded dramatically, with investigations into new areas of mycobacterial growth, replication, metabolism, physiology, drug susceptibility, and virulence, most of the problems in tuberculosis control that existed in 2000 are still with us today.
The good news is that the advances in mycobacterial genetics are beginning to be reflected in exciting recent developments. New diagnostic approaches can determine drug resistance within a few hours, promising new drugs are progressing through the pipeline and into the clinic, and a range of newly developed vaccines are being evaluated. It is an exciting time as the fruits of 30 years of intensive genetic investigation are finally beginning to emerge.
Written by leading experts in the field, Molecular Genetics of Mycobacteria, Second Edition:
Discusses key areas of current research in mycobacterial genetics.
Explains the genetics of the physiology, metabolism, and drug sensitivities of Mycobacterium tuberculosis.
Provides a resource to learn about genetic approaches for manipulating Mycobacterium tuberculosis.
Presents an invaluable handbook for anyone interested in mycobacterial genetics or wishing to enter the field of research into Mycobacterium tuberculosis or other mycobacterial species.
This book is an invaluable resource for anyone interested in the molecular genetics and molecular biology of mycobacteria.