Cramer S.C., Nudo R.J. (eds.) Brain Repair After Stroke

Cambridge: Cambridge University Press, 2010. — 307 p.Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.
Includes basic science and clinical applications, giving readers a complete view on the topic Includes expertise from internationally renowned authors, giving readers an authoritative overview Includes clinical trial and translational aspects of the topic in order to define new therapies that medical professionals can use to reduce disability after strokeMotor map plasticity: a neural substrate for improving motor function after stroke
Molecular mechanisms of neural repair after stroke
Behavioral influences on neuronal events after stroke
Post-stroke recovery therapies in animals
Environmental effects on functional outcome after stroke
Functional and structural MR imaging of brain reorganization after stroke
Stroke recovery in non-human primates: a comparative perspective
Issues in translating stroke recovery research from animals to humans
Brain events in the acute period of stroke in relation to subsequent repair
Changes in cortical excitability and interhemispheric interactions after stroke
Human brain mapping of the motor system after stroke
Recovery from aphasia: lessons from imaging studies
Brain mapping of attention and neglect after stroke
Depression and its effects after stroke
Epidemiology of stroke recovery
Issues in clinical trial methodology for brain repair after stroke
Neuropharmacology in stroke recovery
Robotic approaches to stroke recovery
Electromagnetic approaches to stroke recovery
Intensive physical therapeutic approaches to stroke recovery
Cognitive approaches to stroke recovery
Electrical stimulation approaches to stroke recovery
Growth factors as treatments for stroke
Cellular approaches to stroke recovery