Babashah S. (Ed.) Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology

Cham, Switzerland: Springer International Publishing, 2015. — 560 p. — ISBN: 978-3-319-21029-2, 978-3-319-21030-8.Introduces emerging concepts in cancer stem cell biology and advances our understanding of potential cancer stem cell-based approaches for the development of therapeutic strategies in oncology
Provides a platform for cancer researchers to obtain new perspectives and insightful information regarding the potential role of cancer stem cells in the future of clinical oncology
Differing from other books on the topic, this book is a tremendous resource for both academic and clinical investigatorsThe concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides strong support for the principal functions of these cells in tumorigenesis. This has represented the potential of cancer stem cells in the development of novel and innovative tools for the treatment of metastatic tumors. This book aims to offer a broad framework for obtaining insight into the state-of-the-art knowledge on cancer stem cell biology and highlight the therapeutic implications of these cells in the future of clinical oncology.Cancer Stem Cells: A Quick Walk Through the Concepts
Cellular Plasticity, Cancer Stem Cells and Metastasis
Cytokine Networks and Cancer Stem Cells
Implications of CXCR4/CXCL12 Interaction for Cancer Stem Cell Maintenance and Cancer Progression
Non-coding RNAs in Cancer and Cancer Stem Cells
Self-Renewal Pathways in Mammary Stem Cells and Carcinogenesis
Breast Cancer Stem Cells
Lung Cancer Stem Cells
Colorectal Cancer Stem Cells
Pancreatic Cancer Stem Cells
Glioblastoma Cancer Stem Cells
Head and Neck Cancer Stem Cells
Leukemic and Lymphoid Stem Cells
Leukemic Stem Cells in Acute Lymphoblastic Leukemia
Targeting Key Stemness-Related Pathways in Human Cancers
Targeting Cancer Stem Cells and the Tumor Microenvironment
Cancer Stem Cells and Chemoresistance: Strategies to Overcome Therapeutic Resistance
Cancer Stem Cells and Tumor Radioresistance
Therapeutic Implications of Cancer Stem Cell: Challenges and Opportunities in Translational Studies