Springer International Publishing, Switzerland, 2017. — 187 p. — ISBN10: 3319457985
The synthesis of molecular radiotracers in parallel with recent advances in hybrid imaging has made it possible to study and characterize cardiac anatomy, function, perfusion, metabolism, and innervation in vivo, with exceptional accuracy. The ability to image the shift in the primary source of myocardial energy production from fatty acids toward glucose utilization in the setting of reduced blood flow has helped explain the pathophysiology of hibernation and myocardial viability, as well as management of patients with chronic ischemic left ventricular dysfunction and heart failure for the assessment of myocardial viability. The neuronal component of the myocardium, however, has been sparingly evaluated. This might be an inadvertent oversight, or an apt omission due to its interaction with the abnormalities produced by other myocardial compartments, that have been more easily measured.
Anatomy and Molecular Basis of Autonomic Innervation of the Heart
Neural Control of Cardiac Function in Health and Disease
Chemistry and Biology of Radiotracers Designed to Target Changes in the Myocardial Sympathetic and Parasympathetic Nervous Systems as a Function of Disease or Treatment
Neuronal Imaging in Heart Failure
PET Imaging and Quantitation of Cardiac Innervation
Neuronal Imaging and Reverse Remodeling
Neuronal Imaging, Ventricular Arrhythmias, and Device Therapy in Heart Failure
Cardiac Sympathetic Innervation and Ablation of Ventricular Tachycardia
Dysautonomia: From the Brain Disorders to Neuropathies and Including Diabetes
Cardiac Transplantation: Denervation, Reinnervation, and Myocardial Blood Flow