Humana Press, 2015. — 804 p. — ISBN: 1493918036, 9781493918034.
Includes cutting-edge techniques in cancer epigenetic research
Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts
This volume shares technologies that detect common epigenetic changes which are very important in the early detection, progression, and prognosis of cancer as well as the design of new therapeutic tools against cancer cells. Beginning with a bit of background on epigenetic mechanisms, Cancer Epigenetics: Risk Assessment, Diagnosis, Treatment, and Prognosis continues with cancer specific type epigenetic change, methods and technologies used for detecting epigenetic changes, factors that influence epigenetic changes in cancer, as well as a final section on future directions in the field. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detailed implementation advice that guarantees easily reproducible results.
Comprehensive and practical, Cancer Epigenetics: Risk Assessment, Diagnosis, Treatment, and Prognosis provides the most up-to-date knowledge of epigenetics and its implication in cancer prevention by risk assessment and screening and cancer control by treatment.
Cancer Epigenetics: An Introduction
Community Resources and Technologies Developed Through the NIH Roadmap Epigenomics Program
Epigenome-Wide Association Studies (EWAS): Past, Present, and Future
Epigenetic Biomarkers in Liver Cancer
Cancer Type-Specific Epigenetic Changes: Gastric Cancer
Beyond the Island: Epigenetic Biomarkers of Colorectal and Prostate Cancer
Prostate Cancer Epigenome
CpG Island Hypermethylation as a Biomarker for the Early Detection of Lung Cancer
Analysis of DNA Methylation in Pancreatic Cancer: An Update
Epigenetics of Urothelial Carcinoma
Epigenetics of Prostate Cancer
Methylation Profile Landscape in Mesothelioma: Possible Implications in Early Detection, Disease Progression, and Therapeutic Options
Techniques to Access Histone Modifications and Variants in Cancer
Single Base Resolution Analysis of 5-Methylcytosine and 5-Hydroxymethylcytosine by RRBS and TAB-RRBS
Quantitative DNA Methylation Analysis for Epigenotyping of Colorectal Cancer
Histone Modifications Associated with Cancer Cell Migration and Invasion
Aberrant Epigenetic Modifications in Radiation-Resistant Head and Neck Cancers
Cancer-Associated Infectious Agents and Epigenetic Regulation
Toxicoepigenomics and Cancer: Implications for Screening
Human Papilloma Virus (HPV) Modulation of the HNSCC Epigenome
Epigenetic Regulation of HIV, AIDS, and AIDS-Related Malignancies
Epigenetics of Colorectal Cancer
Epigenetics in Breast and Prostate Cancer
Epigenetic Inhibitors
Use of Epigenetic Modulators as a Powerful Adjuvant for Breast Cancer Therapies
Epigenetic Approaches in Glioblastoma Multiforme and Their Implication in Screening and Diagnosis
Detection of Circulatory MicroRNAs in Prostate Cancer
Identification and Characterization of Small-Molecule Inhibitors of Lysine Acetyltransferases
Epigenetic Regulation in Biopsychosocial Pathways
Viral Epigenetics
P53 Tumor Suppression Network in Cancer Epigenetics
Promoter Hypermethylation as a Biomarker in Prostate Adenocarcinoma
Sequencing the Cancer Methylome
Global DNA Methylation Profiling Technologies and the Ovarian Cancer Methylome
Recent Progress in the Discovery of Epigenetic Inhibitors for the Treatment of Cancer
At the Crossroad Between Obesity and Gastric Cancer
Detection of Epigenetic Aberrations in the Development of Hepatocellular Carcinoma
Specific Type Epigenetic Changes in Cervical Cancers
Epigenetics in Head and Neck Cancer
Epigenetic Therapy for Colorectal Cancer
Epigenetics of Gastric Cancer