Fribley A.M. (Ed.) Targeting Oral Cancer

Springer International Publishing, 2016. — 302 p. — ISBN: 978-3-319-27645-8, 978-3-319-27647-2.Provides up-to-date information on the oral cancer patient population and treatment options
Examines the value of a variety of biomarkers
Describes breaking developments and new drug discoveriesThis book provides research-oriented care providers with up-to-date information on the oral cancer patient population, the ways in which we are treating them, and the scientific approaches being pursued in order to improve survival and reduce treatment-related morbidity. The text is organized into three sections covering epidemiology and management, cancer development and biomarkers, and breaking developments and novel approaches for drug discovery. The first section includes discussion of the emerging role of HPV in oral cancer and explains the surgical, chemotherapy and radiation approaches to treatment. Aspects such as molecular progression, the role of cancer stem cells in tumor development, and the value of various biomarkers are then examined. The final section is devoted to the latest advances and covers, among other topics, current clinical trials, emerging drug targets, and targeting of the unfolded protein response and of mediators of coagulation.Assessing the Changing Oral and Pharyngeal Cancer Demographic in the United States
The Emerging Role of HPV in Head and Neck Cancer
Oral Cancer: Location, Staging, Surgical Management, and Outcomes
Chemotherapy in Head and Neck Squamous Cell Cancer
Molecular Signaling in Oral Cancer Invasion and Metastasis
Cancer Stem Cells in the Biology and Treatment of Head and Neck Squamous Cell Carcinoma
HNSCC Biomarkers Derived from Key Processes of Cancerogenesis
Emerging Molecular Targets in the Treatment of Head and Neck Squamous Cell Carcinoma
Immunotherapy in Head and Neck Cancers
The Unfolded Protein Response as a Therapeutic Target for Head and Neck Squamous Cell Carcinoma
Targeting Coagulation Mediators in Head and Neck Cancer
Mucosal Therapy for Potentially Malignant Diseases and OSCC