Wiley-VCH Verlag GmbH & Co.KGaA, Weinheim, Germany, 2004. — 387 p. — ISBN: 3527307753
This first book dedicated to the topic relates the known physiological functions of porins to their molecular structure and mechanism, as documented by various in vitro and in vivo methods, including the generation of null mutants in mice.
For the first time, it brings together biophysical evidence with studies performed in a cellular context, presenting a unified picture of the fundamental importance of porins for cellular function.
With 16 contributions by an interdisciplinary team of leading porin researchers, this reference is essential reading for every molecular or structural biologist with an interest in this essential protein family.
Regulation of Porin Gene Expression by the Two-component Regulatory System EnvZ/OmpR
The Structures of General Porins
Role of Bacterial Porins in Antibiotic Susceptibility of Gram-negative Bacteria
Porins of the Outer Membrane of Pseudomonas aeruginosa
Regulation of Bacterial Porin Function
Reconstitution of General Diffusion Pores from Bacterial Outer Membranes
OmpA/OprF: Slow Porins or Channels Produced by Alternative Folding of Outer Membrane Proteins
Drug Efflux and Protein Export through Channel-tunnels
Structure–Function Relationships in Sugar-specific Porins
Functional Reconstitution of Specific Porins
Energy-coupled Outer Membrane Iron Transporters
Structural and Functional Aspects of the Vitamin B 12 Receptor BtuB
Structure and Function of Mitochondrial (Eukaryotic) Porins
Mitochondrial Porins in Mammals: Insights into Functional Roles from Mutant Mice and Cells
Gene Family Expression and Multitopological Localization of Eukaryotic Porin/Voltage Dependent Anion-selective Channel (VDAC): Intracellular Trafficking and Alternative Splicing
Function of the Outer Mitochondrial Membrane Pore (Voltage-dependent Anion Channel) in Intracellular Signaling