McCandless D.W. Epilepsy. Animal and human correlations

Springer, 2012. — 525 p.This volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent fi ndings from animal to human studies, and to potential human studies, is emphasized where possible. This volume is designed to facilitate translation and be synoptic in nature. The arrangement of epilepsy chapters is in two parts whenever possible: animal studies, and related human studies. Each chapter has a similar organizational format. The chapters have a brief introductory section, followed by clinical descriptions. Animal studies with a bearing on human clinical issues are presented. The rationale for future human clinical investigations based on animal results is clearly presented when available. Translation is an important consideration in such a complicated field as epilepsy, and its facilitation is critical.