Kenny P.A. The Biology of Cancer: Stages of Cancer Development

Chelsea House Publishers, 2007. — 136 p.In a clear and accessible manner, Stages of Cancer Development follows the evolution of cancer from a single genetically altered cell, through the stages of hyperplasia, dysplasia, carcinoma in situ, to full-blown cancer. This book explores the evolution of cancer from a single genetically altered cell through all stages od development to a potentially fatal disease. Cancer begins with a loss of control over cell division, or hyperplasia. Genetic changes in cancerous cells lead to an excess of cells and to a disruption of their organisation, a process called dysplasia. In the next stage, carcinoma in situ, the growing tumor is more agressive but is still confined to the location where it first began to grow. The transition to an invasive malignant tumor- where the cancer cells begin to invade more deeply into the tissue of origin- may then follow. At that stage the tumor is at risk of spreading throughout the body in a process called metastasis. Understanding how cancer begins and develops is vital to understanding the disease. This book breaks down this complex topic in a clear and approachable manner.Cancer: A Historical Perspective
Oncogenes
Tumor Suppressors
Angiogenesis
Stages of Cancer Progression
Metastasis
Cancer Detection and Diagnosis
After a Positive Diagnosis: Treatment and Cure
If Treatment Fails
Future Perspectives