Nature 2016 №7601, May 05 Volume 533

Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.FeatureThe Material Code. Machine-learning techniques could revolutionize how materials science is done.
Silent no more
Article
Direct detection of the 229Th nuclear clock transition
Principles underlying sensory map topography in primary visual cortex
Research News
Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance
Letter
Resolved atomic lines reveal outflows in two ultraluminous X-ray sources
Polar metals by geometric design
Machine-learning-assisted materials discovery using failed experiments
Scalable and sustainable electrochemical allylic C–H oxidation
Chondritic xenon in the Earth’s mantle
The genetic program for cartilage development has deep homology within Bilateria
Topology of ON and OFF inputs in visual cortex enables an invariant columnar architecture
Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
Unique human immune signature of Ebola virus disease in Guinea
A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges
EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells
Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells
Ubiquitination independent of E1 and E2 enzymes by bacterial effectors
Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
Toolbox
The Struggle with Image Glut
Futures
The Museum Of Nothing
A sense of enterprise
The leap to industry
Academic return
Engagement upgrade
Bavarian biotech
Building an innovator
The geography of discovery
Donor drugs
Comment
Industry-funded academic inventions boost innovation
Starting up and spinning out: The changing nature of partnerships between pharma and academia aligning needs
Pioneering government-sponsored drug repositioning collaborations: progress and learning
Why we need risk innovation