John Wiley & Sons, Ltd, UK, 2016. – 304 p. – ISBN: 111860525X
Biocatalysts are increasingly used by chemists engaged in fine chemical synthesis within both industry and academia. Today, there exists a huge choice of high–tech enzymes and whole cell biocatalysts, which add enormously to the repertoire of synthetic possibilities.
Practical Methods for Biocatalysis and Biotransformations 3 will be a companion book to Practical Methods for Biocatalysis and Biotransformations (2009) and Practical Methods for Biocatalysis and Biotransformations 2 (2012). Following the successful format of the two volumes, it will be a how–to guide focusing on commercially available enzymes and strains of microorganisms that are readily obtained from culture collections. The source of starting materials and reagents, hints, tips and safety advice (where appropriate) will be given to ensure, as far as possible, that the procedures are reproducible. Comparisons to alternative methodology will be given and relevant references to the primary literature will be cited.
Contents include:Considerations for the Application of Process Technologies in Laboratory- and Pilot-Scale Biocatalysis for Chemical Synthesis
Cytochrome P450 (CYP) Progress in Biocatalysis for Synthetic Organic Chemistry
Use of Hydrolases and Related Enzymes for Synthesis
Non-Redox Lyases and Transferases for C-C, C-O, C-S, and C-N Bond Formation
Oxidations
Reductions
Halogenation and Dehalogenation
Cascade Reactions
Biocatalysis for Industrial Process Development