Johnson Norman A. Darwinian detectives. Revealing the Natural History of Genes and Genomes

Oxford University Press, 2007. — 220 p.Biology is often viewed today as a bipartisan field, with molecular level genetics guiding us into the future and natural history (including ecology, evolution, and conservation biology,) chaining us to a descriptive scientific past. In Darwinian Detectives, Norman Johnson bridges this divide, revealing how the tried and true tools of natural history make sense of the newest genomic discoveries. Molecular scientists exploring newly sequenced genomes have stumbled upon quite a few surprises, including that only one to ten percent of the genetic material of animals actually codes for genes. What does the remaining 90-99% of the genome do? Why do some organisms have a much lower genome size than their close relatives? What were the genetic changes that were associated with us becoming human? As molecular biologists uncover these and other new mysteries, evolutionary geneticists are searching for answers to such questions. Norman Johnson captures the excitement of the hunt for our own genetic history. Through lively anecdotes, he explores how researchers detect natural selection acting on genes and what this genetic information tells us about human origins.Natural selection:
Negative selection and the Neural Theory of Molecular Evolution
Detecting Positive Selection
Balancing Selection and Disease
Human Origins and Evolution:
Finding Our Roots: Did Eve Know Adam?
Who Were the Neanderthals?
Are We the Third Chimpanzee?
What Are the Genetic Differences, That Made Us Human?
Clicks, Genes and Languages.
Who Let the Dog In? The Domestication of Animals And Plants.
Size Matters: Toward Understanding the Natural History of Genomes.