Kourounakis P.N., Rekka E. (Eds.) Advanced Drug Design and Development: A Medicinal Chemistry Approach

New York: Ellis Horwood. – 2005. – 150 p. The Department of Pharmaceutical-Medicinal Chemistry, School of Pharmacy, Aristotelian University of Thessaloniki, organizes, every other year, a graduate seminar in advanced medicinal chemistry, with international participation, in Thessaloniki. The purpose of this seminar is to help young and ambitious pharmaceutical scientists in this field by updating their knowledge and informing them about the new trends in our science, through the presentations of renowned invited speakers. It is also aimed to create a forum for exchange of ideas in medicinal chemistry, in a different informal environment, bringing internationally recognized medicinal chemists closer to their Greek colleagues. Chemistry Approach, is a collection of lectures by most of the invited speakers in our second seminar. We hope that this book will be a source of inspiration to all young medicinal chemists, providing examples in drug design from various pharmacochemical approaches.Structure-activity studies and drug design with antagonists at histamine H2 receptors
Acetylcholine, GABA and excitatory amino acid receptors inneurodegenerative disorders
Physicochemical properties and drug action: alternative QSAR methods
Biotransformation of drugs in man: characterization and prediction
The role of computational chemistry in molecular modeling
The importance of labelling of bioactive compounds in the development of new drugs
Epilogue — closing remarks: trends in and future of medicinal chemistry