8th edition. — Saunders, 2013. — 1896 p. — ISBN: 978-0-323-08593-9.
Boasting a worldwide reputation as the leading text in allergy and immunology, Middleton's Allergy continues its steadfast tradition of providing comprehensive coverage of state-of-the-art basic science, as well as authoritative guidance on the clinical concepts of day-to-day diagnosis and management of allergic disorders. Offering timely information that’s suited for clinicians and researchers alike, Middleton’s Allergy, 8th Edition is a user-friendly and versatile source for the knowledge you need to provide optimal care to your patients!
Basic Sciences Underlying Allergy and ImmunologyInnate Immunity
Adaptive Immunity
Immunoglobulin Structure and Function
Immune Tolerance
Cytokines in Allergic Inflammation
Cellular Adhesion in Inflammation
Chemokines
The Complement System
Lipid Mediators of Hypersensitivity and Inflammation
Molecular Biology and Genetic Engineering
Signal Transduction
Biology of Lymphocytes
Antigen-Presenting Dendritic Cells
Biology of Mast Cells and Their Mediators
Biology of Basophils
Biology of Eosinophils
Biology of Neutrophils
Biology of Monocytes and Macrophages
Airway Epithelial Cells
Noncontractile Functions of Airway Smooth Muscle
Pathophysiology of Allergic Inflammation
Genetics and Epigenetics of Allergic Diseases and Asthma
Immunobiology of IgE and IgE Receptors
Neuronal Control of Airway Function in Allergy
Resolution of Allergic Inflammation
Aerobiology and AllergensThe Structure and Function of Allergens
Aerobiology of Outdoor Allergens
Indoor Allergens
Preparation and Standardization of Allergen Extracts *
Air Pollution: Indoor and Outdoor
Particulate and Pollen Interactions
Effect of the Food Matrix and Processing on the Allergenic Activity of Foods
The SkinStructure of the Skin and Cutaneous Immunology
Atopic Dermatitis
Contact Dermatitis
Urticaria and Angioedema
Hereditary Angioedema and Bradykinin-Mediated Angioedema
Immune Complex–Mediated Diseases
The EyeAllergic and Immunologic Diseases of the Eye
Respiratory TractThe Nose and Control of Nasal Airflow
Nasal Provocation Testing
Allergic and Nonallergic Rhinitis
Rhinosinusitis and Nasal Polyps
Development, Structure, and Physiology in Normal Lung and in Asthma
Respiratory Tract Mucosal Immunology
Airway Smooth Muscle Function in Asthma: Extracellular Matrix and Airway Remodeling
Airway Mucus and the Mucociliary System
Epidemiology of Asthma and Allergic Airway Diseases
Ontogeny of Immune Development and Its Relationship to Allergic Diseases and Asthma
Asthma Pathogenesis
Mouse Models of Allergic Airways Disease
Diagnosis of Asthma in Infants and Children
Management of Asthma in Infants and Children
Diagnosis of Asthma in Adults
Management of Asthma in Adolescents and Adults
Emergency Treatment and Approach to the Patient with Acute Asthma
Approach to the Patient with Exercise-Induced Bronchoconstriction *
Asthma and Allergic Diseases during Pregnancy
Occupational Allergy and Asthma
Pathology of Asthma
Allergic Bronchopulmonary Aspergillosis and Hypersensitivity Pneumonitis
Immunologic Nonasthmatic Diseases of the Lung
Approach to the Patient with Chronic Cough
Bronchial Challenge Testing
Lung Imaging
Aerosols and Aerosol Drug Delivery Systems
Gastrointestinal TractGastrointestinal Mucosal Immunology
Eosinophilic Gastrointestinal Disorders
Systemic DiseaseClinical Significance of Immunoglobulin E
In Vivo Methods for the Study and Diagnosis of Allergy
Approach to the Patient with Recurrent Infections
Primary Immunodeficiency Diseases
Human Immunodeficiency Virus and Allergic Disease
Laboratory Tests for Allergic and Immunodeficiency Diseases
Eosinophilia and Eosinophil-Related Disorders
Mastocytosis
Anaphylaxis
Insect Allergy
Drug Allergy
Hypersensitivity to Aspirin and Other Nonsteroidal Antiinflammatory Drugs
Reactions to Foods
Reactions to Food and Drug Additives
Oral Food Challenge Testing
Food Allergy Management
Adverse Reactions to Vaccines for Infectious Diseases
TherapeuticsAllergen Control for Prevention and Management of Allergic Diseases
Injection Immunotherapy for Inhalant Allergens
Sublingual Immunotherapy for Inhalant Allergens
Principles of Pharmacotherapeutics
Pharmacogenomics of Asthma Therapies
Adherence
Anti-Immunoglobulin E Therapy
Cytokine-Specific Therapy in Asthma
Histamine and H1 Antihistamines
Inhaled β2-Agonists
Theophylline and Phosphodiesterase Inhibitors
Anticholinergic Therapies
The Chromones: Cromolyn Sodium and Nedocromil Sodium
Glucocorticosteroids
Antileukotriene Therapy in Asthma
Unconventional Theories and Unproven Methods in Allergy
Complementary and Alternative Medicine
Appendix A. CD Molecules
Appendix B. Internet Resources for Allergy and Immunology Professionals