Esser K. (ed.) Human Fungal Pathogens

Berlin: Springer, 2014. - 298 p.Whereas plant and insect infections are commonly caused by fungi, only a small minority of the vast diversity of fungal species is pathogenic to humans. Despite this, fungal infections cause considerable morbidity and mortality worldwide. This volume is dedicated to the biology, clinical presentation and management of invasive fungal infections. Major pathogenic fungi are introduced by world-leading experts and the basic principles of fungal virulence are reviewed in the light of new results and experimental technologies that offer unprecedented insights into invasive infections caused by Aspergillus, Candida, Cryptococcus, Pneumocystis and Mucorales. In parallel, the clinical presentation of invasive fungal infections and current approaches to their diagnosis and treatment are summarized to provide an overview of human pathogenic fungi, linking pathogen biology to the clinical presentation of disease.Front MatteriFrom Commensal to Pathogen: Candida albicans8
Aspergillus fumigatus: Saprotroph to Pathogen
Systems Biology Approaches to Understanding and Predicting Fungal VirulenceReceptor–Ligand Interactions in Fungal Infections
Macrophages in the Immune Response Against Cryptococcus
T Cell Responses in Fungal Infections
Molecular Mechanisms of Histoplasma Pathogenesis
Visualizing Immune Responses in Fungal Infections: Established and Novel Methods
Mucosal Immunology in Candida albicans InfectionInvasive Aspergillosis in the Intensive Care Unit
Molecular Epidemiology of Pneumocystis Outbreaks
Infections Caused by Mucorales
Diagnostics of Fungal InfectionsTherapeutic Strategies in Fungal Infections
Antifungal Pharmacokinetics