DOE Human Genome Program Primer on Molecular Genetics

U.S. Department of Energy, 1992. — 44 p.
June 1992 DOE Human Genome 1991-92 Program Report.
Series: DOE Human Genome Program
The primer is intended to be an introduction to basic principles of molecular genetics pertaining to the genome project.DNA
Genes
Chromosomes
Mapping and Sequencing the Human Genome
Mapping Strategies
Genetic Linkage Maps
Physical Maps
Low-Resolution Physical Mapping
Chromosomal map
cDNA map
High-Resolution Physical Mapping
Macrorestriction maps: Top-down mapping
Contig maps: Bottom-up mapping
Sequencing Technologies
Current Sequencing Technologies
Sequencing Technologies Under Development
Partial Sequencing to Facilitate Mapping, Gene Identification
End Games: Completing Maps and Sequences; Finding Specific Genes
Model Organism Research
Informatics: Data Collection and Interpretation
Collecting and Storing Data
Interpreting Data
Mapping Databases
Sequence Databases
Nucleic Acids (DNA and RNA)
Proteins
Impact of the Human Genome Project