Yousef M., Allmer J. miRNomics: MicroRNA Biology and Computational Analysis

Humana Press, 2014 — 333 p. — (Methods in Molecular Biology 1107) — ISBN: 978-1-62703-748-8 (eBook), 978-1-62703-747-1 (Hardcover).In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective. These include methods and techniques ranging from miRNA biogenesis, their biological function, computational analyses to their medical implications and applications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, miRNomics: MicroRNA Biology and Computational Analysis seeks to aid scientists in the further study into miRNA research and statistics.Introduction to MicroRNAs in Biological Systems
The Role of MicroRNAs in Biological Processes
The Role of MicroRNAs in Human Diseases
Introduction to Bioinformatics
MicroRNA and Noncoding RNA-Related Data Sources
High-Throughput Approaches for MicroRNA Expression Analysis
Introduction to Machine Learning
Introduction to Statistical Methods for MicroRNA Analysis
Computational and Bioinformatics Methods for MicroRNA Gene Prediction
Machine Learning Methods for MicroRNA Gene Prediction
Functional, Structural, and Sequence Studies of MicroRNA
Computational Methods for MicroRNA Target Prediction
MicroRNA Target and Gene Validation in Viruses and Bacteria
Gene Reporter Assay to Validate MicroRNA Targets in Drosophila S2 Cells
Computational Prediction of MicroRNA Function and Activity
Analysis of MicroRNA Expression Using Machine Learning
MicroRNA Expression Landscapes in Stem Cells, Tissues, and Cancer
Master Regulators of Posttranscriptional Gene Expression Are Subject to Regulation
Use of MicroRNAs in Personalized Medicine