Drug Discovery Today 2013 v.18 №15-16

London, UK.: Elsevier. — 116 p.Since its launch in 1996, Drug Discovery Today has been at the cutting edge of the science underpinning drug discovery and development. Drug Discovery Today delivers highly current reviews to the readers, not only addressing the rapid scientific developments in drug discovery associated technologies, but also the management, commercial and regulatory issues that increasingly play a part in how R&D is planned, structured and executed.The future is here: tumour profiling in day-to-day clinical practice
Charlotte R. Lemech, Hendrik-Tobias ArkenauDesigned multiple ligands in metabolic disease research: from concept to platform
W. Gattrell, C. Johnstone, S. Patel, C. Sambrook Smith, A. Scheel, M. SchindlerPharmacokinetics and the drug–target residence time concept
Göran Dahl, Tomas AkerudInhibition of proteases as a novel therapeutic strategy in the treatment of metabolic, inflammatory and functional diseases of the gastrointestinal tract
Maciej Sałaga, Marta Sobczak, Jakub FichnaThe Tox21 robotic platform for the assessment of environmental chemicals – from vision to reality
Matias S. Attene-Ramos, Nicole Miller, Ruili Huang, Sam Michael, Misha Itkin, Robert J. Kavlock, Christopher P. Austin, Paul Shinn, Anton Simeonov, Raymond R. Tice, Menghang XiaMatched Molecular Pair Analysis in drug discovery
Alexander G. Dossetter, Edward J. Griffen, Andrew G. LeachSystematic characterization of structure–activity relationships and ADMET compliance: a case study
Austin B. Yongye, José L. Medina-FrancoIs autologous chondrocyte implantation (ACI) an adequate treatment option for repair of cartilage defects in paediatric patients?
Marietta Kaszkin-BettagNon-peptidyl insulin mimetics as a potential antidiabetic agent
Rakesh P. Nankar, Mukesh DobleMolecular understanding of curcumin in diabetic nephropathy
Vivian Soetikno, Kenji Suzuki, Punniyakoti T. Veeraveedu, Somasundaram Arumugam, Arun P. Lakshmanan, Hirohito Sone, Kenichi WatanabeModel-based drug discovery: implementation and impact
Sandra A.G. Visser, Malin Aurell, Rhys D.O. Jones, Virna J.A. Schuck, Ann-Charlotte Egnell, Sheila A. Peters, Lena Brynne, James W.T. Yates, Rasmus Jansson-Löfmark, Beesan Tan, Marie Cooke, Simon T. Barry, Andrew Hughes, Ulf BredbergCurrent status of liposomal porphyrinoid photosensitizers
Paulina Skupin-Mrugalska, Jaroslaw Piskorz, Tomasz Goslinski, Jadwiga Mielcarek, Krystyna Konopka, Nejat DüzgüneşCysteamine: an old drug with new potential
Martine Besouw, Rosalinde Masereeuw, Lambert van den Heuvel, Elena Levtchenko