Drug Discovery Today 2013 v.18 №07-08

London, UK.: Elsevier. — 112 p.Since its launch in 1996, Drug Discovery Today has been at the cutting edge of the science underpinning drug discovery and development. Drug Discovery Today delivers highly current reviews to the readers, not only addressing the rapid scientific developments in drug discovery associated technologies, but also the management, commercial and regulatory issues that increasingly play a part in how R&D is planned, structured and executed.Open Innovation in Drug Discovery research comes of age
Duncan B. JuddDesign principles for innovative workspaces to increase efficiency in pharmaceutical R&D: lessons learned from the Novartis campusSmall and colorful stones make beautiful mosaics: fragment-based chemogenomics
Chris de Graaf, Henry F. Vischer, Gerdien E. de Kloe, Albert J. Kooistra, Saskia Nijmeijer, Martien Kuijer, Mark H.P. Verheij, Paul J. England, Jacqueline E. van Muijlwijk-Koezen, Rob Leurs, Iwan J.P. de EschTorching the Haystack: modeling fast-fail strategies in drug development
Dennis W. Lendrem, B. Clare LendremInjectable implants for the sustained release of protein and peptide drugs
Priyanka Agarwal, Ilva D. RupenthalTranscriptional data: a new gateway to drug repositioning?
Francesco Iorio, Timothy Rittman, Hong Ge, Michael Menden, Julio Saez-RodriguezThe holistic integration of virtual screening in drug discovery
Yusuf Tanrikulu, Björn Krüger, Ewgenij ProschakMultiple active receptor conformation, agonist efficacy and maximum effect of the system: the conformation-based operational model of agonism
David Roche, Debora Gil, Jesús GiraldoChronic autoimmune-mediated inflammation: a senescent immune response to injury
Bert A. ’t Hart, Paulina Chalan, Gerrit Koopman, Annemieke M.H. BootsNovel antitussive strategies
Jaymin B. Morjaria, Rebecca S. Dickinson, Alyn H. MoriceQuinolines: a new hope against inflammation
Soumita Mukherjee, Manojit PalBrain tumor immunotherapy: seeing the brain in the body
Lois A. LampsonαC helix displacement as a general approach for allosteric modulation of protein kinases
Lorenzo Palmieri, Giulio Rastelli