Drug Discovery Today 2013 v.18 №05-06

London, UK.: Elsevier. — 116 p.Since its launch in 1996, Drug Discovery Today has been at the cutting edge of the science underpinning drug discovery and development. Drug Discovery Today delivers highly current reviews to the readers, not only addressing the rapid scientific developments in drug discovery associated technologies, but also the management, commercial and regulatory issues that increasingly play a part in how R&D is planned, structured and executed.The surprising link between hair curlers and drug discovery
Mark MurckoIs poor research the cause of the declining productivity of the pharmaceutical industry? An industry in need of a paradigm shift
Frank Sams-DoddThe promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so
Douglas B. Kell, Paul D. Dobson, Elizabeth Bilsland, Stephen G. OliverThree-dimensional cell culture: the missing link in drug discovery
Susan Breslin, Lorraine O’DriscollAdvances and strategies in discovery of new antibacterials for combating metabolically resting bacteria
Dirk Bald, Anil KoulBiological network inference for drug discovery
Paola Lecca, Corrado PriamiFour disruptive strategies for removing drug discovery bottlenecks
Sean Ekins, Chris L. Waller, Mary P. Bradley, Alex M. Clark, Antony J. WilliamsSocial networks, web-based tools and diseases: implications for biomedical research
Fabricio F. CostaDelivering the promise of miRNA cancer therapeutics
Diane M. Pereira, Pedro M. Rodrigues, Pedro M. Borralho, Cecília M.P. RodriguesRecent advances in topical ophthalmic drug delivery with lipid-based nanocarriers
Li Gan, Jing Wang, Min Jiang, Hanah Bartlett, Defang Ouyang, Frank Eperjesi, Jianping Liu, Yong GanExpanding medicinal chemistry space
Andy Barker, Jason G. Kettle, Thorsten Nowak, J. Elizabeth PeaseLow molecular weight heparins copies: are they considered to be generics or biosimilars?
Paola Minghetti, Francesco Cilurzo, Silvia Franzé, Umberto M. Musazzi, Manuela Itri